Chromosomes and Gene Expression

Chromosomes and Gene Expression

eLife reviews research ranging from transcription and RNA processing to epigenetics and chromatin biology. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    A whole-organism landscape of X-inactivation in humans

    Björn Gylemo, Maike Bensberg, Colm E Nestor
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Chromosomes and Gene Expression

    Distal Gene Expression Governed by Lamins and Nesprins via Chromatin Conformation Change

    Haihui Zhang, Zhengyang Lei ... Peiwu Qin
    Not revised
    Reviewed Preprint v1
    • Useful
    • Inadequate
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Deep sequencing of yeast and mouse tRNAs and tRNA fragments using OTTR

    Hans Tobias Gustafsson, Lucas Ferguson ... Oliver J Rando
    A recently developed RNA cloning protocol efficiently captures both intact and fragmented tRNAs.
    1. Chromosomes and Gene Expression
    2. Evolutionary Biology

    Post-fertilization transcription initiation in an ancestral LTR retrotransposon drives lineage-specific genomic imprinting of ZDBF2

    Hisato Kobayashi, Tatsushi Igaki ... Kazuki Kurimoto
    A novel mechanism for the establishment of species-specific imprinting emerged through LTR insertion and post-fertilization activation.
    1. Developmental Biology
    2. Chromosomes and Gene Expression

    Linage priming and cell type proportioning depends on the interplay between stochastic and deterministic factors

    William M Salvidge, Chris Brimson ... Christopher RL Thompson
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Chromosomes and Gene Expression

    Genome organization by SATB1 binding to base-unpairing regions (BURs) provides a scaffold for SATB1-regulated gene expression

    Yoshinori Kohwi, Xianrong Wong ... Terumi Kohwi-Shigematsu
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Structural Biology and Molecular Biophysics
    2. Chromosomes and Gene Expression

    Structural mechanism of strand exchange by the RAD51 filament

    Luay Joudeh, Robert E Appleby ... Luca Pellegrini
    Not revised
    Reviewed Preprint v1
    • Landmark
    • Compelling
    1. Chromosomes and Gene Expression

    MagIC-Cryo-EM, structural determination on magnetic beads for scarce macromolecules in heterogeneous samples

    Yasuhiro Arimura, Hide A Konishi, Hironori Funabiki
    A technique that enables single-particle cryo-EM analysis of targets on a magnetic bead and a particle curation method that helps structural classification of small particles has been developed.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Transcriptional coregulation in cis around a contact insulation site revealed by single-molecule microscopy

    Maciej A Kerlin, Ilham Aboulfath-Ladid ... Antoine Coulon
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Chromosomes and Gene Expression

    Nuclear and cytosolic J-domain proteins provide synergistic control of Hsf1 at distinct phases of the heat shock response

    Carmen Ruger-Herreros, Lucia Svoboda ... Bernd Bukau
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Compelling
Load more

Highlights

    1. Chromosomes and Gene Expression
    2. Structural Biology and Molecular Biophysics

    Navigating the secrets of COMPASS

    Karolin Luger, Jonathan W Markert
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Reality check for transposons

    Julie Brind'Amour, Dixie L Mager
    1. Chromosomes and Gene Expression

    Painting chromosomes in the nucleus

    Cori K Cahoon, Diana E Libuda

Senior editors

  1. Yamini Dalal
    National Cancer Institute, United States
  2. Adèle L Marston
    University of Edinburgh, United Kingdom
  3. Lori Sussel
    University of Colorado Anschutz Medical Campus, United States
  4. See more editors