Abstract

A mathematical model of competition between two species for two growth-limiting, essential (complementary) resources in the unstirred chemostat is considered. The existence of a positive steady-state solution and some of its properties are established analytically. Techniques include the maximum principle, the fixed point index, and numerical simulations. The simulations also seem to indicate that there are regions in parameter space for which a globally stable positive equilibrium occurs and that there are other regions for which the model admits bistability and even multiple positive equilibria.

MSC codes

  1. 35K55
  2. 35J65
  3. 92A17

Keywords

  1. chemostat
  2. essential or complementary resources
  3. steady-state solution
  4. fixed point index
  5. numerical simulation

Get full access to this article

View all available purchase options and get full access to this article.

References

1.
H. Amann, Fixed point equations and nonlinear eigenvalue problems in ordered Banach spaces, SIAM Rev., 18 (1976), pp. 620–709.
2.
Mary Ballyk, Gail Wolkowicz, An examination of the thresholds of enrichment: a resource‐based growth model, J. Math. Biol., 33 (1995), 435–457
3.
Mary Ballyk, Gail Wolkowicz, Exploitative competition in the chemostat for two perfectly substitutable resources, Math. Biosci., 118 (1993), 127–180
4.
B. C. Baltzis and A. G. Fredrickson, Limitation of growth rate by two complementary nutrients: Some elementary and neglected considerations, Biotechnol. Bioeng., 31 (1988), pp. 75–86.
5.
J. Baxley, H. Thompson, Nonlinear boundary value problems and competition in the chemostat, Nonlinear Anal., 22 (1994), 1329–1344
6.
G. Butler, G. Wolkowicz, A mathematical model of the chemostat with a general class of functions describing nutrient uptake, SIAM J. Appl. Math., 45 (1985), 138–151
7.
G. Butler, G. Wolkowicz, Exploitative competition in a chemostat for two complementary, and possibly inhibitory, resources, Math. Biosci., 83 (1987), 1–48
8.
Le Dung, Hal Smith, A parabolic system modeling microbial competition in an unmixed bio‐reactor, J. Differential Equations, 130 (1996), 59–91
9.
A. Fredrickson, Gregory Stephanopoulos, Microbial competition, Science, 213 (1981), 972–979
10.
Jack Hale, Paul Waltman, Persistence in infinite‐dimensional systems, SIAM J. Math. Anal., 20 (1989), 388–395
11.
S. R. Hansen and S. P. Hubbell, Single nutrient microbial competition: Agreement between experimental and theoretical forecast outcomes, Science, 207 (1980), pp. 1491–1493.
12.
W. Harder and L. Dijkhuizen, Strategies of mixed substrate utilization in microorganisms, Philos. Trans. R. Soc. London B., 297 (1982), pp. 459–480.
13.
Sze Hsu, Kuo Cheng, S. Hubbell, Exploitative competition of microorganisms for two complementary nutrients in continuous cultures, SIAM J. Appl. Math., 41 (1981), 422–444
14.
S. B. Hsu, S. Hubbell, and P. Waltman, A mathematical theory for single‐nutrient competition in continuous cultures of micro‐organisms, SIAM J. Appl. Math., 32 (1977), pp. 366–383.
15.
Sze Hsu, P. Waltman, On a system of reaction‐diffusion equations arising from competition in an unstirred chemostat, SIAM J. Appl. Math., 53 (1993), 1026–1044
16.
J. A. Leon and D. B. Tumpson, Competition between two species for two complementary or substitutable resources, J. Theoret. Biol., 50 (1975), pp. 185–201.
17.
Bingtuan Li, Hal Smith, How many species can two essential resources support?, SIAM J. Appl. Math., 62 (2001), 336–366
18.
Bingtuan Li, Gail Wolkowicz, Yang Kuang, Global asymptotic behavior of a chemostat model with two perfectly complementary resources and distributed delay, SIAM J. Appl. Math., 60 (2000), 2058–2086
19.
Sergei Pilyugin, Paul Waltman, Competition in the unstirred chemostat with periodic input and washout, SIAM J. Appl. Math., 59 (1999), 1157–1177
20.
Murray Protter, Hans Weinberger, Maximum principles in differential equations, Springer‐Verlag, 1984x+261, Corrected reprint of the 1967 original
21.
D. J. Rapport, An optimization model of food selection, Am. Nat., 105 (1971), pp. 575–587.
22.
Hal Smith, Paul Waltman, Competition in an unstirred multi‐dimensional chemostat, World Sci. Publishing, River Edge, NJ, 1996, 475–486
23.
Hal Smith, An application of monotone systems theory to a model of microbial competition, Lecture Notes in Pure and Appl. Math., Vol. 176, Dekker, New York, 1996, 293–307
24.
Hal Smith, Paul Waltman, The theory of the chemostat, Cambridge Studies in Mathematical Biology, Vol. 13, Cambridge University Press, 1995xvi+313, Dynamics of microbial competition
25.
Joseph So, Paul Waltman, A nonlinear boundary value problem arising from competition in the chemostat, Appl. Math. Comput., 32 (1989), 169–183, Mathematical biology
26.
Joel Smoller, Shock waves and reaction‐diffusion equations, Grundlehren der Mathematischen Wissenschaften [Fundamental Principles of Mathematical Science], Vol. 258, Springer‐Verlag, 1983xxi+581
27.
D. Tilman, Resource Competition and Community Structure, Princeton University Press, Princeton, NJ, 1982.
28.
Paul Waltman, Stephen Hubbell, Sze Hsu, Theoretical and experimental investigations of microbial competition in continuous culture, Lecture Notes in Pure and Appl. Math., Vol. 58, Dekker, New York, 1980, 107–152
29.
Jian Wu, Yan Li, Stability of steady‐state solutions of the competition model in the chemostat, Systems Sci. Math. Sci., 7 (1994), 256–260
30.
J. Wu, Global bifurcation of coexistence state for the competition model in the chemostat, Nonlinear Anal., 39 (2000), 817–835
31.
Jianhua Wu, Gail Wolkowicz, A system of resource‐based growth models with two resources in the unstirred chemostat, J. Differential Equations, 172 (2001), 300–332
32.
Eberhard Zeidler, Nonlinear functional analysis and its applications. I, Springer‐Verlag, 1986xxi+897, Fixed‐point theorems; Translated from the German by Peter R. Wadsack